Neither one of these suggestions worked, but I do have some more information that should be useful.
When she opens an Excel spreadsheet it opens another copy of Excel with the file title "Personal.xls"
Her Personal.xls file lives in "C:\Documents and Settings\CThompson\Application Data\Microsoft\Excel\XLSTART"
Her Macro Security is set to "Low".
When she tries to use a macro she gets an error message that states:
"The file could not be accessed. Try one of the following:
Make sure the specified file exists.
Make sure the folder that contains the file is not read only.
Make sure the file name does not contain any of the following character's: < > ? [ ] : PERSONAL.XLS or *
Make sure the file/path name doesn't contain more than 218 characters.
One more tid bit of information.
Just before this started I installed "Office XP Add-in Remove Hidden data", "rhdtool.exe".
Does this help?